PUBLICATIONS

References and Links to Papers

  1. Shi L, Ermis R, Garcia A, Telgenhoff D, Aust D., “Degradation of Human Collagen Isoforms by Clostridium Collagenase and the Effects of Degradation Products on Cell Migration.” International Wound Journal, 2010 (PMID: 20529148)

  2. Garcia A.M., Ladage M.L, & Padilla, P.A., “Use of Time Lapse Microscopy to Visualize Anoxia-Induced Suspended Animation in C. elegans Embryos.” Journal of Visual Experiments, 2012 (PMID: 23242305)

  3. Padilla P.A., Garcia A.M., Ladage M.L., Toni, L.S., “C. elegans: An Old Genetic Model Can Learn New Epigenetic Tricks.” Integrative and Comparative Biology, 2014 (PMID: 24861810)

  4. Garcia A.M., Ladage M.L., Dumesnil D.R., Zaman K., Shulaev V., Azad R.K, Padilla P.A., “Glucose Induces Sensitivity to Oxygen Deprivation and Modulates Insulin/IGF-1 Signaling and Lipid Biosynthesis in Caenorhabditis elegans.” Genetics, 2015 (PMID: 25762526)

  5. Ladage M.L., King S.D., Burks D.J., Quan D.L., Garcia A.M., Azad R.K., Padilla P.A., “Glucose and Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans.” G3 Genetics, 2016 (PMID: 27507791)

  6. Nakano S.J., Siomos A.K., Garcia A.M., Nguyen H., SooHoo M., Galambos C., Nunley K., Stauffer B.L., Sucharov C.C., Miyamoto S.D., “Fibrosis-related Gene Expression in Single Ventricle Heart Disease.” J. Pediatrics, 2017 (PMID: 29050751)

  7. Sucharov C.C., Miyamoto S.D., Garcia A.M., “Circulating microRNAs as Biomarkers in Pediatric Heart Diseases”, Progress in Pediatric Cardiology, 2018 (https://www.sciencedirect.com/science/article/pii/S1058981317300668)

  8. Toni LS*, Garcia AM*, Jeffrey DA, Jiang X, Stauffer BL, Miyamoto SD, Sucharov CC., “Optimization of phenol-chloroform RNA extraction.” MethodsX, 2018 *Authors contributed equally (PMID: 29984193)

  9. Garcia A.M., Nakano S.J., Karimpour-Fard  A., Nunley K., Blain-Nelson P., Stafford N.M., Stauffer B.L., Sucharov C.C., Miyamoto S.D., “Phosphodiesterase-5 is Elevated in Failing Single Ventricle Myocardium and Affects Cardiomyocyte Remodeling in vitro.” Circulation Heart Failure, 2018 (PMID: 30354365)

  10. Garcia AM*, Allawzi A*, Tatman P, Hernandez-Lagunas L, Swain K, Mouradian G, Bowler R, Karimpour-Fard A, Sucharov CC, Nozik-Grayck E., “R213G polymorphism in SOD3 protects against bleomycin-induced inflammation and attenuates induction of proinflammatory pathways.” Physiological Genomics, 2018 *Authors contributed equally (PMID: 30004839)

  11. Nakano S.J., Walker J.S., Walker L.A., Li X., Du Y., Miyamoto S.D., Sucharov C.C., Garcia A.M., Mitchell M.B., Ambardekar A.V., Stauffer B.L., “Increased Myocyte Calcium Sensitivity in End-Stage Pediatric Dilated Cardiomyopathy.”, Am J Physiol Heart Circ Physiol., 2019 (PMID: 31625780)

  12. Garcia A.M., Beatty J.T., Nakano S.J., “Heart Failure in Single Ventricle Congenital Heart Disease: Physiologic and Molecular Considerations.” Am J Physiol Heart Circ Physiol., 2020 (PMID: 32108525)

  13. Garcia A.M.*, McPhaul J.C.*, Sparagna G.S., Patel S., Sucharov C.C., Stauffer B.L., Miyamoto S.D., and Chatfield K.C., “Alteration of Cardiolipin Biosynthesis and Remodeling in Single Right Ventricle Congenital Heart Disease.” Am J Physiol Heart Circ Physiol., 2020 *Authors contributed equally (PMID: 32056460)

  14. Rubinstein J., Woo J.G., Garcia A.M., Alsaied T., Li J., Lunde P.K., Moore R., Laasmaa M., Sammons A., Mays W.A., Miyamoto S.D., Louch W.E., Veldtman G., “Probenecid improves cardiac function in subjects with a Fontan circulation and augments cardiomyocyte calcium homeostasis.” Pediatr. Cardiol., 2020 (PMID: 32770262)

  15. Wall JB, Garcia AM, Jacobsen RM, Miyamoto SD, “Important Considerations in Pediatric Heart Failure.” Current Cardiology Reports, 2020 (PMID: 32910348)

  16. Ohlstrom D., Hernandez-Lagunas L., Garcia A.M., Allawzi A., Karimpour-Fard A., Carpenter T., Sucharov C.C., Nozik-Grayck E., “MicroRNA regulation post-bleomycin due to the R213G extracellular superoxide dismutase variant is predicted to suppress inflammatory and immune pathways.”, Physiol Genomics, 2020 (PMID: 32421439)

  17. Jeffrey DA, Pires Da Silva J, Garcia AM, Jiang X, Karimpour-Fard A, Toni LS, Lanzicher T, Pena BC, Miyano CA, Nunley K, Korst A, Sbaizero O, Taylor M, Miyamoto SD, Stauffer BL, Sucharov CC, “Serum Circulating Proteins from Pediatric Dilated Cardiomyopathy Patients Cause Pathologic Remodeling and Cardiomyocyte Stiffness”, JCI Insight, 2021 (PMID: 34383712)

  18. Pires Da Silva J, Baybayon-Grandgeorge AN, Pietra AE, and Garcia AM, “Serum metabolic profiling identifies key differences between patients with single ventricle heart disease and healthy controls.” Int. J. Transl. Med., 2022

  19. Baybayon-Grandgeorge AN, Pietra AE, Miyamoto SD, and Garcia AM, “Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome”, J. Cardiovasc Dev Dis 2022 (PMID: 35621863)

  20. Tsai CW, Rodriguez MX, Van Keuren AM, Phillips CB, Shushunov HM, Lee JE, Garcia AM, Ambardekar AV, Cleveland JC, Reisz JA, Proenza C, Chatfield KC, Tsai MF, “Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex.” Mol Cell 2022 (PMID: 36206740)

  21. Sparagna GC, Jonscher RL, Shuff SR, Phillips EK, Wilson CE, Woulfe KC, Garcia AM, Stauffer BL, Chatfield KC, “Linoleate-Enrichment of Mitochondrial Cardiolipin Molecular Species Is Developmentally Regulated and a Determinant of Metabolic Phenotype.” Biology (Basel), 2022 (PMID: 36671725)

  22. Garcia AM, Toni LS, Miyano CA, Sparagna GS, Jonscher R, Phillips EK, Karimpour-Fard A, Chapman HL, Baybayon-Grandgeorge AN, Pietra AE, Selner E, Chatfield KC, Stauffer BL, Sucharov CC, Miyamoto SD, “Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single Ventricle Congenital Heart Disease,” JACC Basic Transl Sci. 2023 (PMID: 37034285)

  23. Pires Da Silva J, Padilla PA, Garcia AM, “Editorial: The intersection of gene regulation and metabolism in cardiovascular disease,” Front Genet.2023 (PMID: 37701624)

  24. Garcia AM*, ^, Pietra AE*, Turner ME, Pires Da Silva J, Baybayon-Grandgeorge AN, Sparagna GC, Jeffrey DA, Stauffer BL, Sucharov CC^, Miyamoto SD, “Cardiomyocyte Metabolic Remodeling in Single Ventricle Heart Disease is Abrogated with Phosphodiesterase-5 Inhibitor Therapy,” under review, *Authors contributed equally, ^Co-corresponding authors

  25. Lewis CV, Garcia AM, Burciaga SD, Posey JN, Jordan M, Nguyen TN, Stenmark KR, Mickael C, Sul C, Delaney C, Nozik ES, “Redistribution of SOD3 expression due to R213G polymorphism affects pulmonary interstitial macrophage reprogramming in response to hypoxia,” Physiol Genomics, 2024 (PMID: 39311838)

  26. Iguidbashian J, Zakrzewski J, Lu L, Garcia AM, Khailova L, Deng X, Plenter R, La Rosa F, Nakano SJ, Lynch K, Jaggers J, Davison J, Stone ML, “Sphingosine-1-phosphate improves myocardial contractility and mitochondrial function in a novel murine ex vivo perfusion and transplantation model,” J Thorac Cardiovasc Surg, 2025 (PMID: 40043942)